Flufenamic Acid-Promoted the Coupling of Epoxides and CO₂ to Form Cyclic Carbonates

Title:Flufenamic Acid-Promoted the Coupling of Epoxides and CO₂ to Form Cyclic Carbonates

Volume: 18 Issue: 10

Author(s): Ling Wu, Qingpeng Zeng, Pinghua Hu, Taoqi Zong and Fengtian Wu*

Affiliation:

• Jiangxi Province Key Laboratory of Polymer Micro/Nano Manufacturing and Devices, East China University of Technology, Nanchang 330013,China

Keywords: Flufenamic acid, epoxide, CO2, cyclic carbonate, TBAB, phenylacetylene.

Abstract: The process of hydrogen bond donor accelerating the cycloaddition of epoxides with CO2 is a green conversion. In this text, commercial drug flufenamic acid which contains O-H and N-H groups is introduced to promote the coupling. The reaction is capable of tolerating a relatively wide range of groups with the aid of catalytic system flufenamic acid/TBAB. Moreover, the reaction mechanism is proposed on the basis of reported literatures.

Cite this article as:

Wu Ling, Zeng Qingpeng, Hu Pinghua , Zong Taoqi and Wu Fengtian*, Flufenamic Acid-Promoted the Coupling of Epoxides and CO₂ to Form Cyclic Carbonates, Letters in Organic Chemistry 2021; 18 (10) . https://dx.doi.org/10.2174/1570178617999201110115648