Abstract
An efficient synthesis of 2-substituted Quinazolin-4(3H)-ones has been developed from isatoic anhydride with various amidoximes by using a recyclable polymer-supported sulphonic acid catalyst. Excellent functional group compatibility and high yields are the important features of this protocol.
Keywords: 2-substituted quinazolin-4 (3H)-ones, wang resin-supported sulfonic acid, recyclable catalyst, isatoic anhydride, amidoxime, anti-bacterial.
Graphical Abstract
Letters in Organic Chemistry
Title:An Efficient Synthesis of 2-Substituted Quinazolin-4(3H)-ones by Using Recyclable Wang Resin Supported Sulfonic Acid Catalyst
Volume: 18 Issue: 10
Author(s): K. Kalyani and Srinivasa Reddy Kallam*
Affiliation:
- Technology Development Centre, Custom Pharmaceutical Services, Dr. Reddy’s Laboratories Ltd, Hyderabad 500 049, Telangana,India
Keywords: 2-substituted quinazolin-4 (3H)-ones, wang resin-supported sulfonic acid, recyclable catalyst, isatoic anhydride, amidoxime, anti-bacterial.
Abstract: An efficient synthesis of 2-substituted Quinazolin-4(3H)-ones has been developed from isatoic anhydride with various amidoximes by using a recyclable polymer-supported sulphonic acid catalyst. Excellent functional group compatibility and high yields are the important features of this protocol.
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Cite this article as:
Kalyani K. and Kallam Reddy Srinivasa*, An Efficient Synthesis of 2-Substituted Quinazolin-4(3H)-ones by Using Recyclable Wang Resin Supported Sulfonic Acid Catalyst, Letters in Organic Chemistry 2021; 18 (10) . https://dx.doi.org/10.2174/1570178617999201109203731
DOI https://dx.doi.org/10.2174/1570178617999201109203731 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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