Abstract
Background: Several quinones are on the pharmaceutical market as drugs for the treatment of several diseases.
Objective: The aim of this review was to provide an overview of the quinones that have become drugs for several therapeutic applications.
Methods: We have comprehensively and critically discussed all the information available in the literature about quinone-based drugs.
Results: In this review, the various aspects of the chemistry and biochemistry of these drugs are highlighted, including their repositioning, drug combination and their new uses.
Conclusion: A number of studies related to quinone drugs for different pharmaceutical uses show that the interest in new applications is still increasing in recent years.
Keywords: Atovaquone, buparvaquone, parvaquone, mitomycins, doxorubicin, valrubicin, mitoxantrone.
Graphical Abstract