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Review Article

绝经后骨质疏松症和益生菌

卷 22, 期 7, 2021

发表于: 27 October, 2020

页: [816 - 822] 页: 7

弟呕挨: 10.2174/1389450121666201027124947

价格: $65

摘要

绝经后骨质疏松症（PMO）的特点是骨量低和骨组织结构恶化，且绝经后妇女发生骨折的风险增加。这是由于更年期后雌激素生成不足，导致骨骼重塑过程中的失衡，其中吸收/形成更倾向于重新选择，从而导致骨质流失。它在受影响的妇女中引起高发病率和严重的健康并发症。当前的PMO治疗具有许多不良副作用，甚至增加了发生肿瘤的可能性。因此，需要安全有效的替代疗法。益生菌是由有益微生物组成的膳食补充剂，当以足够的量施用时，可以为宿主带来健康益处。最近的科学证据表明肠道菌群与骨骼健康之间存在联系。这篇综述讨论了骨骼重塑的过程以及肠道菌群对宿主骨骼代谢的作用。此外，它总结了益生菌对PMO动物模型以及绝经后妇女的最新研究。

关键词: 绝经后骨质疏松症（PMO，益生菌，骨骼重塑，肠道菌群，骨骼健康，动物模式。

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