Abstract
An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole derivatives via a three-component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedicarboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.
Keywords: Pyanocarbazole, hydroxycarbazole, isocyanides, dialkylacetylenedicarboxylates, carbazole, multicomponent reaction.
Graphical Abstract
Letters in Organic Chemistry
Title:Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanidebased Three-component Reaction
Volume: 18 Issue: 9
Author(s): Visarapu Malathi, Pedavenkatagari Narayana Reddy*Pannala Padmaja*
Affiliation:
- Department of Chemistry, School of Science, Gitam University, Hyderabad (T.S),India
- Centre for Semio Chemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad,India
Keywords: Pyanocarbazole, hydroxycarbazole, isocyanides, dialkylacetylenedicarboxylates, carbazole, multicomponent reaction.
Abstract: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole derivatives via a three-component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedicarboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.
Export Options
About this article
Cite this article as:
Malathi Visarapu , Reddy Narayana Pedavenkatagari *, Padmaja Pannala *, Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanidebased Three-component Reaction, Letters in Organic Chemistry 2021; 18 (9) . https://dx.doi.org/10.2174/1570178617999201020215852
DOI https://dx.doi.org/10.2174/1570178617999201020215852 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Privileged Scaffolds Targeting Bromodomain-containing Protein 4
Current Topics in Medicinal Chemistry Receptor Tyrosine Kinases: The Main Targets for New Anticancer Therapy
Current Drug Targets Delivery Systems for RNA Interference Therapy: Current Technologies and Limitations
Current Gene Therapy Aging and Inflammation: Etiological Culprits of Cancer
Current Aging Science Production of Retroviral Vectors: Review
Current Gene Therapy Combined Modality Treatment of Limited Stage Small Cell Carcinoma of the Lung
Reviews on Recent Clinical Trials Dibenzofurans from Lichens – A Pharmacological Overview
Current Topics in Medicinal Chemistry Regulation of Bcl-2 Family Proteins by Posttranslational Modifications
Current Molecular Medicine Chemoinformatic Analysis of Biologically Active Macrocycles
Current Topics in Medicinal Chemistry The Impact of Molecularly Targeted Therapies Upon the Understanding of Leukemogenesis and the Role of Hematopoietic Stem Cell Transplantation in Acute Promyelocytic Leukemia
Current Stem Cell Research & Therapy A Phase I Study of OMN54 (Aneustat™) in Patients with Advanced Malignancies
Clinical Cancer Drugs NRG1-ErbB Lost in Translation: A New Paradigm for Lung Cancer?
Current Medicinal Chemistry Baseline Levels of Interleukine-6, Tumor-Necrosis Factor-Alpha and C-Reactive Protein in Treatment Naive Human Immunodeficiency Virus Infected Patients-A Study from a Tertiary-Care Hospital in Eastern India
Current Biomarkers (Discontinued) STAT3 and Its Phosphorylation are Involved in HIV-1 Tat-Induced Transactivation of Glial Fibrillary Acidic Protein
Current HIV Research Functional Glyco-Affinity Precipitation/Capturing for Enhanced Affinity Proteomics
Current Proteomics Meet Our Regional Editor
Anti-Cancer Agents in Medicinal Chemistry RhoGEFs in Cell Motility: Novel Links Between Rgnef and Focal Adhesion Kinase
Current Molecular Medicine Paclitaxel Formulations: Challenges and Novel Delivery Options
Current Drug Delivery Recent Progress in Research on Ribosome Inactivating Proteins
Current Protein & Peptide Science Editorial [Hot topic: Modifying Cardiovascular Risk Factors: Epidemiology and Characteristics of Smoking-Related Cardiovascular Diseases (Executive Editor: Aurelio Leone)]
Current Pharmaceutical Design