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Current Topics in Medicinal Chemistry

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ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

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Review Article

Synthesis and Biological Activity Study of Tanshinone Derivatives: A Literature and Patent Review

Author(s): He Huang, Chuanjun Song* and Junbiao Chang

Volume 20, Issue 28, 2020

Page: [2520 - 2534] Pages: 15

DOI: 10.2174/1568026620666200922115109

Price: $65

Abstract

Tanshinones are a class of bioactive compounds present in the Chinese herbal medicine Danshen (Salvia miltiorrhiza Bunge), containing among others, abietane diterpene quinone scaffolds. Chemical synthesis and biological activity studies of natural and unnatural tanshinone derivatives have been reviewed in this article.

Keywords: Danshen, Tanshinone, Chemical synthesis, Structural modification, Biological activity, Herbal medicine.

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