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Endocrine, Metabolic & Immune Disorders - Drug Targets

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ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

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Review Article

MicroRNAs for Diagnosis and Treatment of Colorectal Cancer

Author(s): Haitao Mei and Yugang Wen*

Volume 21, Issue 1, 2021

Published on: 18 August, 2020

Page: [47 - 55] Pages: 9

DOI: 10.2174/1871530320999200818134339

Price: $65

Abstract

Colorectal cancer (CRC) is the third most common cancer worldwide, with high morbidity and mortality rates. The diagnosis and treatment of CRC have the most significant value for disease- free survival. Early diagnosis and early surgical resection are generally considered to be the most effective ways to reduce CRC mortality. In the past few years, many researchers have focused on the role of microRNAs in different tumors, making the functions of microRNAs gradually clear. The present study reviews the role of microRNAs in the diagnosis and treatment of colorectal cancer. Compared with the usual diagnosis methods and biomarker, circulating microRNAs can be promising new effective biomarkers for CRC diagnosis and treatment.

Keywords: CRC, diagnosis and treatment, liquid biopsy, miRNA, combined-biomarkers testing, tumorigenesis.

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