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Mini-Reviews in Medicinal Chemistry

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ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

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Review Article

Research Development, Optimization and Modifications of Anti-cancer Peptides

Author(s): Zhi-Gang Sun*, Liang-Hui Zhao, Stacy Mary Yeh, Zhi-Na Li and Xin Ming*

Volume 21, Issue 1, 2021

Published on: 29 July, 2020

Page: [58 - 68] Pages: 11

DOI: 10.2174/1389557520666200729163146

Price: $65

Abstract

Anti-cancer peptides play an important role in the area of cancer inhibition. A variety of anti- cancer peptides have emerged through the extraction and structural modification of peptides from biological tissues. This review provides the research background of anti-cancer peptides, the introduction of the mechanism of anti-cancer peptides for inhibition of cancers, the discovery and development along with optimization and modifications of these peptides in the clinical application. In conclusion, it can be said that anti-cancer peptides will play a major role in the future oncologic clinic.

Keywords: Anti-cancer peptides, modifications, mechanisms, progress, development, optimization.

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