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Current Drug Safety

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ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

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Case Report

A Case of Acute Generalized Exanthematous Pustulosis by Cefixime with Oral Mucosal Involvement

Author(s): Ramanachary Namoju*, Mohammed Ismail, Vinay Kumar Golla, Tejaswini Bamini, Thanmaya Lakshmi Akarapu and Deepika Baloju

Volume 15, Issue 3, 2020

Page: [236 - 239] Pages: 4

DOI: 10.2174/1574886315999200729144555

Price: $65

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction characterized by the development of numerous sterile and non-follicular pustules on an erythematous base with no or minimal mucous membrane involvement associated with fever and leucocytosis. Cefixime is a cephalosporin-type beta-lactam antibiotic commonly used for the management of several infections. The Cefixime-induced AGEP cases are known to be rare. Here, we present the case report of a 26-year old female who developed Cefixime-induced AGEP with mucosal membrane involvement. To the best of our knowledge, this is the first case to report the mucosal membrane involvement in Cefixime-induced AGEP. We are presenting this case report to draw the attention on the existence and plethora of symptoms of Cefixime-induced AGEP hoping that the clinicians will reckon these in their differential diagnosis and implement the appropriate management strategies for this rare adverse event in their clinical practice.

Keywords: Cefixime, acute generalized exanthematous pustulosis, mucous membrane involvement, non-follicular pustules, severe cutaneous adverse reaction, erythematous eruption.

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Graphical Abstract

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