Abstract
Background: Helicobacter pylori is a slow-growing micro-aerophilic gram-negative organism found in the stomach and duodenum. It is also associated with a number of stomach-duodenal diseases.
Material and Methods: There are invasive and non-invasive methods to detect Helicobacter pylori infections. In a 13-months period, 101 patients with clinical signs of infection confirmed by biopsy and Rapid Urease test as well as a culture were included in this study.
Results: There were significant correlations between breath urease test, anti-Helicobacter pylori serum IgG and IgA as well as fecal Helicobacter pylori Ag with the gold-standard method, (P=0.001) Moreover, there was a significant correlation between Monocytosis (P= 0.05) and goldstandard method.
Conclusion: Based on studies conducted on patients with Helicobacter pylori infection, noninvasive diagnostics methods can be useful in the diagnosis of Helicobacter infections rather than evaluating anti-Helicobacter pylori serum IgM and also increased blood monocytes could be a reliable confirmation for detection. Furthermore, Monocytosis must be considered as a Helicobacter pylori infection at the first step in an area with a high infected percentage.
Keywords: Helicobacter pylori, diagnosis methods, monocytosis, infection, Leukocytosis , gram-negative.
Infectious Disorders - Drug Targets
Title:Comparison of Helicobacter pylori Detection Methods: It’s Association with Leukocytosis and Monocytosis
Volume: 20 Issue: 6
Author(s): Monireh Rahimkhani*, Alireza Mordadi, Kiana Kazemian and Hourieh Khalili
Affiliation:
- Faculty of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran,Iran
Keywords: Helicobacter pylori, diagnosis methods, monocytosis, infection, Leukocytosis , gram-negative.
Abstract:
Background: Helicobacter pylori is a slow-growing micro-aerophilic gram-negative organism found in the stomach and duodenum. It is also associated with a number of stomach-duodenal diseases.
Material and Methods: There are invasive and non-invasive methods to detect Helicobacter pylori infections. In a 13-months period, 101 patients with clinical signs of infection confirmed by biopsy and Rapid Urease test as well as a culture were included in this study.
Results: There were significant correlations between breath urease test, anti-Helicobacter pylori serum IgG and IgA as well as fecal Helicobacter pylori Ag with the gold-standard method, (P=0.001) Moreover, there was a significant correlation between Monocytosis (P= 0.05) and goldstandard method.
Conclusion: Based on studies conducted on patients with Helicobacter pylori infection, noninvasive diagnostics methods can be useful in the diagnosis of Helicobacter infections rather than evaluating anti-Helicobacter pylori serum IgM and also increased blood monocytes could be a reliable confirmation for detection. Furthermore, Monocytosis must be considered as a Helicobacter pylori infection at the first step in an area with a high infected percentage.
Export Options
About this article
Cite this article as:
Rahimkhani Monireh *, Mordadi Alireza , Kazemian Kiana and Khalili Hourieh , Comparison of Helicobacter pylori Detection Methods: It’s Association with Leukocytosis and Monocytosis, Infectious Disorders - Drug Targets 2020; 20 (6) . https://dx.doi.org/10.2174/1871526520666200707113955
DOI https://dx.doi.org/10.2174/1871526520666200707113955 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Patent Selections
Recent Patents on Biomarkers Crystal Structure of a Flavin-dependent Thymidylate Synthase from Helicobacter pylori strain 26695
Protein & Peptide Letters DNA Methylation: An Epigenetic Insight into Type 2 Diabetes Mellitus
Current Pharmaceutical Design In Vivo Roles of CDC25 Phosphatases: Biological Insight into the Anti-Cancer Therapeutic Targets
Anti-Cancer Agents in Medicinal Chemistry Role of Angiopoietin-like 4 (ANGPTL4), a Member of Matricellular Proteins: from Homeostasis to Inflammation and Cancer Metastasis
Current Angiogenesis (Discontinued) Retinoid Related Molecules an Emerging Class of Apoptotic Agents with Promising Therapeutic Potential in Oncology: Pharmacological Activity and Mechanisms of Action
Current Pharmaceutical Design Lipids as Delivery Systems to Improve the Biological Activity of Bioactive Ingredients
Current Nutrition & Food Science TNFα Modulation of Visceral and Spinal Sensory Processing
Current Pharmaceutical Design Base Excision Repair: Contribution to Tumorigenesis and Target in Anticancer Treatment Paradigms
Current Medicinal Chemistry Lysophospholipids: Synthesis and Biological Aspects
Current Organic Chemistry The Endocannabinoid System in the Cancer Therapy: An Overview
Current Medicinal Chemistry Biology of Cox-2: An Application in Cancer Therapeutics
Current Drug Targets Use of Caffeine and Nicotine in People with Schizophrenia
Current Drug Abuse Reviews Plasma-Free Amino Acid Profiling of Nasal Polyposis Patients
Combinatorial Chemistry & High Throughput Screening Targeting Apoptosis Pathway with Natural Terpenoids: Implications for Treatment of Breast and Prostate Cancer
Current Drug Targets Critical Update and Emerging Trends in Imatinib Treatment for Gastrointestinal Stromal Tumor
Reviews on Recent Clinical Trials Has the Two Week Rule Improved Cancer Detection Rates for Gastrointestinal Cancers? A Systematic Literature Review
Current Cancer Therapy Reviews The Effects of Nanoencapsulated Curcumin-Fe3O4 on Proliferation and hTERT Gene Expression in Lung Cancer Cells
Anti-Cancer Agents in Medicinal Chemistry The Role of STAT3 Signaling in Mediating Tumor Resistance to Cancer Therapy
Current Drug Targets Recent Patents on Live Bacteria and their Products as Potential Anticancer Agents
Recent Patents on Anti-Cancer Drug Discovery