Abstract
A wide range of evidence shows that acetylcholinesterase (AChE) inhibitors can
Keywords: donepezil hydrochloride, acetylcholinesterase inhibitors, alzheimer s disease, AChE inhibitors, cortical cholinergic neurotransmission, hepatotxic liability, physostigmine, cholineric enhancement therapy, ACh releasers, M1 M3 Receptor agonists, nicotinic agonists, velnacrine, amiridine, eptastigmine, galanthamine, rivastigmine, metrifonate, huperzine A, donepezil hydrocloride, anti AChE Activity, n alkyl analogs, molecular modeling, receptor dependent docking, crystal structure, BuChE, Brain acetylcholine concentrations, TAK 147, anti inflammatory agents, alzheimer s disease treatment, estrogen replacement therapy, anti oxidants, anti amyloid, galanin receptor antagonist