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Review Article

当前结肠靶向口服给药的薄膜涂层设计

卷 28, 期 10, 2021

发表于: 04 June, 2020

页: [1957 - 1969] 页: 13

弟呕挨: 10.2174/0929867327666200604170048

价格: $65

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摘要

结肠靶向口服给药最近吸引了大量的系统性和局部治疗研究。在结肠给药方法中，薄膜涂层被证明是药物给药系统的有效组成部分，因为它们可以整合多种释放策略，如pH控释、时间控释和酶触发释放。此外，涂层调制、天然膜材料和纳米粒子涂层的研究也在蓬勃发展，具有广阔的应用前景。这篇综述的目的是描述主要的方法，以改善药物交付到结肠在过去的十年。当前薄膜涂层发展的突出重要性将推进剂型设计，并导致高效结肠靶向口服给药系统的发展。

关键词: 结肠给药、薄膜包衣、薄膜调制、天然薄膜、纳米粒子包衣、给药

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