Generic placeholder image

Current Microwave Chemistry

Editor-in-Chief

ISSN (Print): 2213-3356
ISSN (Online): 2213-3364

Research Article

Green Synthesis of Some Novel Imidazole Schiff base Derivatives Under Microwave Irradiation / Reflux Conditions and Evaluations of the Antibacterial Activity

Author(s): Samaneh Eftekhari, Naser Foroughifar*, Sara Hallajian and Alireza Khajeh-Amiri

Volume 7, Issue 3, 2020

Page: [207 - 215] Pages: 9

DOI: 10.2174/2213335607999200520124245

Price: $65

Abstract

Background: Schiff bases are excellent compounds. They were synthesized by condensation of active carbonyl and amines. They were widely used as a substrate in the preparation of industrial compounds as well as pharmaceutical purposes. They exhibit a wide range of biological activities. In this study, based on the importance of Schiff bases, a sustainable synthetic method was developed employing reflux and microwave irradiation.

Objective: The aim is to develop a new synthetic method for imidazole Schiff base derivatives synthesis employing reflux, microwave irradiation, and ethanol as a green solvent.

Methods: Synthesis of imidazole Schiff base derivatives was carried out under reflux and microwave irradiation conditions. Antibacterial activity of imidazole derivatives and standard drugs was examined against two Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis) and two Gramnegative bacteria (Proteus mirabilis, Escherichia coli).

Results: Schiff bases were synthesized in the presence of microwave irradiation and ethanol in high yields 90-98% for 2-4 min. The antibacterial effects of Schiff bases were evaluated against both strains of Gram-positive and Gram-negative.

Conclusion: In this paper, a novel series of imidazole Schiff base derivatives were synthesized using reflux, microwave irradiation, and ethanol. Antibacterial effects were investigated. The excellent advantages of microwave irradiation in the synthesis of imidazole derivatives include reduction of reaction time from an hour to a minute, high product yield. In this study, the measurement of antibacterial activity was also important. Imidazole derivatives with Cl, OH, and CH3 groups showed antibacterial effects.

Keywords: Schiff base, microwave-assisted, microwave irradiation, imidazole schiff base derivatives, antibacterial activity, spectral studies, amine derivatives.

Graphical Abstract

[1]
Kumar, J.; Rai, A.; Raj, V. A Comprehensive Review on the Pharmacological Activity of Schiff Base Containing Derivatives.Organic Medicinal Chem IJ,, 2017, 1, 001-0015.
[2]
Adabiardakani, A.; Hakimi, M.; Karga, H. Cinnamaldehyde Schiff Base Derivatives: A Short Review. World Appl. Program., 2010, 2, 472-476.
[3]
Yousif, E.; Majeed, A.; Al-Sammarrae, K.; Salih, N.; Salimon, J.; Abdullah, B. Metal complexes of Schiff base: Preparation, characterization and antibacterial activity. Arab. J. Chem., 2017, 10, S1639-S1644.
[http://dx.doi.org/10.1016/j.arabjc.2013.06.006]
[4]
Durmus, S.; Dalmaz, A.; Dülger, G.; Kadioglu, D.B. Synthesis of disulphide-Schiff base derivatives and investigations of in vitro antimicrobial activities against some human pathogens. EuroBiotech J., 2017, 1, 230-234.
[http://dx.doi.org/10.24190/ISSN2564-615X/2017/03.06]
[5]
Malik, S.; Jain, B.; Mirza, A.S.; Singh, A.S. Review study on metal complexes synthesized from therapeutically important schiff bases. Pharm. Chem. J., 2016, 3, 119-124.
[6]
Hussain, Z.; Khalaf, M.; Adil, H.; Zageer, D.; Hassan, F.; Mohammed, S.; Yousif, E. Metal complexes of schiff’s bases containing sulfonamides nucleus: A review. Res. J. Pharm. Biol. Chem. Sci., 2016, 7, 1008-1025.
[7]
Sahu, R.; Thakur, D.S.; Kashyap, P. Metal complexes of schiff’s bases containing sulfonamides nucleus: A review. Int J Pharm Sci & Nanotech., 2012, 5, 1757-1764.
[8]
Magar, B.K.; Kirdanta, A.S.; Chondhekar, K.K. Formation of N-salicylidene-p-chloroaniline: A kinetic study. Acta Chim. Pharm. Indica., 2013, 4, 40-46.
[9]
Patel, V.; Trivedi, P.; Gohel, H.; Khetani, D. Synthesis and characterization of schiff base of p-chloro aniline and their metal complexes and their evaluation for antibacterial activity. Int. J. Appl. Biol. Pharm. Technol., 2014, 3, 999-1003.
[10]
Yadav, G.; Jyoti, V. Mani. Modification structure of schiff base compounds. Int. J. Sci. Res. (Ahmedabad), 2012, 4, 1-13.
[11]
Sobola, A.O.; Watkins, G.M.; Van Brecht, B.V.S. Synthesis, characterization and antimicrobial activity of copper (II) complexes of some ortho-substituted aniline schiff bases; Crystal structure of bis(2-methoxy-6-imino) methylphenol copper (II). Complex. S. Afr. J. Chem., 2014, 67, 45-51.
[12]
Pratap Singh, M. Synthesis, characterization and biological activities of Schiff base and it’s transition metal complexes. Int. J. Life Sci. (Kathmandu), 2018, A12, 23-28.
[13]
Shamly, P.; Nelson, M.P.; Antony, A.; Varkey, J.T. Synthesis of salicylaldehyde based schiff bases and their methal complexes in aqueous media-characterization and antibacterial study. Int. J. Recent Sci. Res., 2018, 9, 26566-26570.
[14]
Ejelonu, B.C.; Olagboye, S.A.; Oyeneyin, O.E.; Ebiesuwa, O.E.; Baba, O.E. Synthesis, characterization and antimicrobial activities of sulfadiazine schiff base and phenyl dithiocarbamate mixed ligand metal complexes. Open J. Appl. Sci., 2018, 8, 346-354.
[http://dx.doi.org/10.4236/ojapps.2018.88026]
[15]
Patil, S.; Jadhav, S.D.; Patil, U.P. Natural acid catalyzed synthesis of schiff base under solvent-free condition: As a green approach. Arch. Appl. Sci. Res., 2012, 4, 1074-1078.
[16]
Kumar, A.; Verma, S.; Mishra, A.K.; Kumar, S. Synthesis of some new Schiff bases of Pharmaceutical Interest. Ann Adv Chem., 2017, 1, 53-56.
[http://dx.doi.org/10.29328/journal.aac.1001006]
[17]
Natiq, C.; Al-Hashimi, A.H. Preparation and characterization of some new schiff bases compounds with the study of biological effectiveness. Int. J. Curr. Res. Biosci. Plant Biol., 2016, 3, 127-136.
[http://dx.doi.org/10.20546/ijcrbp.2016.305.020]
[18]
Haddad, H.H. A new schiff base derivatives designed to bind metal ion (Cu, Co): Thermodynamics and biological activity studies. Am. J. Anal. Chem., 2016, 7, 446-451.
[http://dx.doi.org/10.4236/ajac.2016.75041]
[19]
Badwaik, H.R.; Alexander, A.; Sakure, K. Understanding the significance of microwave radiation for the graft copolymerization of acrylamide on carboxymethyl xanthan gum. Curr. Microw. Chem., 2019, 6, 13-22.
[http://dx.doi.org/10.2174/2213335606666190307162901]
[20]
Beniwal, M.; Jain, N. Microwave assisted synthesis, characterization and antimicrobial screening of thiazolidin-4-one substituted pyrazole derivatives. Curr. Microw. Chem., 2019, 6, 44-53.
[http://dx.doi.org/10.2174/2213335606666190722144956]
[21]
Hiremath, P.B.; Kamanna, K. A microwave accelerated sustainable approach for the synthesis of 2-amino-4H-chromenes catalysed by WEPPA: A green strategy. Curr. Microw. Chem., 2019, 6, 30-43.
[http://dx.doi.org/10.2174/2213335606666190820091029]
[22]
Satyanarayana, V.S.V. Rakshit. M.; Sivakumar. A. Microwave-assisted synthesis of 2,4,5-triphenyl-1H-imidazole containing schiff base derivatives with potential antioxidant and anticancer activities. Asian J. Chem., 2012, 23, 1212-1218.
[23]
Gupta, G.K.; Rani, N.; Kumar, V. Microwave assisted synthesis of imidazole – A Review. Mini Rev. Org. Chem., 2012, 9, 270-284.
[http://dx.doi.org/10.2174/1570193X11209030270]
[24]
Patel, N.; Pathan, S.; Soni, H.I. 3,4-dihydropyrimidin-2(1H)-one analogues: Microwave irradiated synthesis with antimicrobial and antituberculosis study. Curr. Microw. Chem., 2019, 6, 61-70.
[http://dx.doi.org/10.2174/2213335606666190724093305]
[25]
Shinde, A.; Zangade, S.; Chavan, S.; Vibhute, Y. Microwave induced synthesis of bis-Schiff bases from propane-1,3-diamine as promising antimicrobial analogs. Org. Commun., 2014, 7, 60-67.
[26]
Naqvi, A.; Shahnawaaz, M.; Rao, A.V.; Seth, D.S.; Sharma, N.K. Synthesis of Schiff bases via enviromentally benign and energy-efficient greener methodologies. E-J. Chem., 2009, 6(S1), S75-S78.
[http://dx.doi.org/10.1155/2009/589430]
[27]
Mobinikhaledi, A.; Forughifar, N.; Kalhor, M. An efficient synthesis of Schiff bases containing benzimidazole moiety catalyzed by transition metal nitrates. Turk. J. Chem., 2010, 34, 367-373.
[28]
Shaygan, S.; Pasdar, H.; Foroughifar, N.; Davallo, M.; Motiee, F. Cobalt (II) complexes with schiff base ligands derived from terephthaldehyde and ortho-substituted anilines: Synthesis, characterization and antibacterial activity. Appl. Sci. (Basel), 2018, 8, 1-12.
[http://dx.doi.org/10.3390/app8030385]
[29]
Mobinikhaledi, A.; Foroughifar, N.; Khanpour, M.; Ebrahimi, S. Synthesis of some novel Schiff bases containing 1,2,4-triazole rings. Eur. J. Chem., 2010, 1(1), 33-36.
[http://dx.doi.org/10.5155/eurjchem.1.1.33-36.5]
[30]
Youmbi Fonkui, T.; Itohan Ikhile, M.; Berka Njobeh, P.; Tantoh Ndinteh, D. Benzimidazole Schif base derivatives: Synthesis, characterization andfantimicrobial activity. BMC Chem., 2019, 13(127), 2-11.
[31]
Latif, M.A.; Tofaz, T.; Chaki, B.M.; Tariqul, H.M.; Saddam Hossain, Md. Kudrat-E-Zhahan, Md. Synthesis, characterization, and biological activity of the schiff base and its Ni(II), Cu(II), and Zn(II) complexes derived from 4-(Dimethylamino)benzaldehyde and S-Benzyldithiocarbazate. Russ. J. Gen. Chem., 2019, 89, 1197-1207.
[http://dx.doi.org/10.1134/S107036321906015X]

Rights & Permissions Print Cite
© 2025 Bentham Science Publishers | Privacy Policy
Request history8.2.27PHP Version358msRequest Duration28MBMemory UsageGET article/{article_id}/{param?}Route
  • warninglog[20:21:19] LOG.warning: Optional parameter $article_id declared before required parameter $request i...
  • warninglog[20:21:20] LOG.warning: trim(): Passing null to parameter #1 ($string) of type string is deprecated ...
  • warninglog[20:21:20] LOG.warning: Function strftime() is deprecated in /home/alphaeurekaselec/public_html/stor...
  • Booting (103ms)time
  • Application (255ms)time
  • 1 x Application (71.21%)
    255ms
    1 x Booting (28.79%)
    103ms
    14 templates were rendered
    • articlearticle.blade.php#?blade
    • includes.article_top_bannerarticle_top_banner.blade.php#?blade
    • includes.article_referencearticle_reference.blade.php#?blade
    • export_citation_formexport_citation_form.blade.php#?blade
    • includes.article_bottom_bannerarticle_bottom_banner.blade.php#?blade
    • includes.inc_related_journalsinc_related_journals.blade.php#?blade
    • includes.inc_related_ebooksinc_related_ebooks.blade.php#?blade
    • includes.journal_rightmenujournal_rightmenu.blade.php#?blade
    • includes.journal_right_bannerjournal_right_banner.blade.php#?blade
    • layouts.appapp.blade.php#?blade
    • layouts._login_access_login_access.blade.php#?blade
    • layouts._header_header.blade.php#?blade
    • layouts._main_menu_main_menu.blade.php#?blade
    • layouts._footer_menu_footer_menu.blade.php#?blade
    uri
    GET article/{article_id}/{param?}
    middleware
    web, check_user_access
    controller
    App\Http\Controllers\ArticleController@GetArticleDetails
    namespace
    App\Http\Controllers
    where
    as
    article
    file
    app/Http/Controllers/ArticleController.php:1974-2510
    36 statements were executed, 4 of which were duplicates, 32 unique. Show only duplicated175ms
    • Connection Establishedalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 9. middleware::check_user_access:24
      • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address (ip_address,visitor_agent,visitor_count, created_on,updated_on) VALUES ('51271243','',1,1740514879,1740514879) ON DUPLICATE KEY UPDATE visitor_count=visitor_count + 1, updated_on=1740514879
      1.97msalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 11. middleware::check_user_access:24
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('51271243','/article/106808',1,1740514879,1740514879)
      220μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#27
      Backtrace
      • 11. middleware::check_user_access:27
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 51271243 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51271243) limit 1
      15.7msalphaeurekaselec_live_10_06_2022UserAccess.php#784
      Bindings
      • 0: 51271243
      • 1: 51271243
      • 2: 51271243
      • 3: 51271243
      • 4: 51271243
      • 5: 51271243
      • 6: 51271243
      • 7: 51271243
      • 8: 51271243
      • 9: 51271243
      • 10: 51271243
      • 11: 51271243
      • 12: 51271243
      • 13: 51271243
      • 14: 51271243
      • 15: 51271243
      Backtrace
      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
    • SELECT at.type_name, p.copyright, p.publisher_location,m.month,y.year, a.publish_on, a.nid article_nid,a.article_id, a.pmid, a.issue_id, a.title, a.abstract,a.podcast,a.altmetric_score,a.altmetric_url,a.kudos_url, a.page_count, a.first_page, a.elocator, a.last_page, i.publication_date, a.file_name, a.file_path, a.doi, a.is_epub,a.epub_type, a.volume_id, a.is_uploaded, a.editor_choice, a.is_epub, j.image_file_name, a.article_no, a.art_type AS article_type, a.supplementary_filename,a.html_filename,a.prc_filename,a.epub_filename, a.graph_abs_lg_filename, a.graph_abs_sm_filename, a.oa_image_lg_filename, a.oa_image_sm_filename, j.journal_banner,a.animated_abstract,a.erratum_in,a.erratum_for, (CASE WHEN a.issue_id =0 THEN j.epub_price ELSE j.price END) AS sell_price, j.epub_price, j.nid AS jour_nid, j.title AS journal_title, j.issn, j.eissn,j.journal_id, j.subtitle AS jour_subtitle, v.volume_id,v.volume_name AS volume, v.year_id, i.title AS issue, i.month_id ,i.type issue_type, j.subtitle,j.formerly_title, ac.subtitle AS epub_title,a.crossmark_enabled,a.text_mining_urls,a.license_urls,a.created, a.receivedate, a.revisedate, a.acceptdate,js.js_title FROM article a LEFT JOIN article_section ac ON a.is_epub = ac.art_sec_id LEFT JOIN journal_section js ON a.js_id = js.js_id LEFT JOIN article_type at ON a.art_type = at.art_type_id LEFT JOIN issue i ON a.issue_id = i.issue_id LEFT JOIN month m ON m.id = i.month_id LEFT JOIN volume v ON v.volume_id = a.volume_id INNER JOIN year y ON y.id = v.year_id INNER JOIN journal j ON j.journal_id = a.journal_id INNER JOIN publisher p ON p.publisher_id = j.publisher_id WHERE a.article_id=106808
      2.15msalphaeurekaselec_live_10_06_2022Article.php#408
      Backtrace
      • 11. app/Models/Article.php:408
      • 12. app/Http/Controllers/ArticleController.php:2515
      • 13. app/Http/Controllers/ArticleController.php:2035
      • 14. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 15. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `journal` where `journal_id` = 144 limit 1
      950μsalphaeurekaselec_live_10_06_2022Journal.php#64
      Bindings
      • 0: 144
      Backtrace
      • 14. app/Models/Journal.php:64
      • 15. app/Http/Controllers/ArticleController.php:2516
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select count(*) as aggregate from (select j.nid as journal_nid,j.flyer_link,j.title ,j.issn,j.eissn,j.keyword, j.journal_id as journal_id, j.subtitle, j.image_file_name,j.description,j.journal_insight_url,j.doi from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where j.journal_status=1 and subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=144) and sj.journal_id!=144 group by `j`.`nid`) as `aggregate_table`
      830μsalphaeurekaselec_live_10_06_2022Subject.php#200
      Backtrace
      • 16. app/Models/Subject.php:200
      • 17. app/Http/Controllers/ArticleController.php:2517
      • 18. app/Http/Controllers/ArticleController.php:2035
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 20. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select j.nid as journal_nid,j.flyer_link,j.title ,j.issn,j.eissn,j.keyword, j.journal_id as journal_id, j.subtitle, j.image_file_name,j.description,j.journal_insight_url,j.doi from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where j.journal_status=1 and subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=144) and sj.journal_id!=144 group by `j`.`nid` order by `j`.`journal_id` asc limit 10 offset 0
      760μsalphaeurekaselec_live_10_06_2022Subject.php#200
      Backtrace
      • 14. app/Models/Subject.php:200
      • 15. app/Http/Controllers/ArticleController.php:2517
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select count(*) as aggregate from (select v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `se`.`ebook_id` inner join `year` as `y` on `y`.`id` = `v`.`year_id` where subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=144) and v.ebook_status='1' and y.year > 2020 group by `v`.`nid`) as `aggregate_table`
      41.19msalphaeurekaselec_live_10_06_2022Subject.php#220
      Backtrace
      • 16. app/Models/Subject.php:220
      • 17. app/Http/Controllers/ArticleController.php:2518
      • 18. app/Http/Controllers/ArticleController.php:2035
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 20. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `se`.`ebook_id` inner join `year` as `y` on `y`.`id` = `v`.`year_id` where subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=144) and v.ebook_status='1' and y.year > 2020 group by `v`.`nid` order by `v`.`ebook_volume_id` desc limit 10 offset 0
      49.69msalphaeurekaselec_live_10_06_2022Subject.php#220
      Backtrace
      • 14. app/Models/Subject.php:220
      • 15. app/Http/Controllers/ArticleController.php:2518
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `keywords` where `article_id` = '106808'
      1.54msalphaeurekaselec_live_10_06_2022Keywords.php#43
      Bindings
      • 0: 106808
      Backtrace
      • 13. app/Models/Keywords.php:43
      • 14. app/Http/Controllers/ArticleController.php:2519
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `article_citation` where `article_id` = '106808'
      2.53msalphaeurekaselec_live_10_06_2022Article.php#1570
      Bindings
      • 0: 106808
      Backtrace
      • 13. app/Models/Article.php:1570
      • 14. app/Http/Controllers/ArticleController.php:2520
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select CONCAT_WS(' ',au.first_name, ' ', ifnull(au.initials,''), ' ', au.last_name) as authors, CONCAT(au.last_name, IFNULL(CONCAT(' ', au.initials), ''), ' ', au.first_name) AS authorsRIS, CONCAT_WS(' ',au.last_name, ' ', ifnull(au.initials,''), ' ', au.first_name) as authorsCiteAs, CONCAT_WS(' ',au.first_name, IFNULL(CONCAT(' ', au.initials), ''), IFNULL(CONCAT(' ', au.last_name), '')) as authorsmodal , `au`.*, `af`.`ror_id`, `af`.`institution`, `af`.`department`, `af`.`country`, `af`.`city`, `af`.`address`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.institution,','),''), ifnull(concat(af.department,','),''), ifnull(concat(af.address,','),''), ifnull(concat(af.city,','),''), ifnull(concat(af.country,','),''), ifnull(concat(af.postal_code,','),''), ifnull(concat(af.phone,','),''), ifnull(concat(af.fax,','),''))) SEPARATOR '|')) as `author_affiliation`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.web_view,','),''))) SEPARATOR '|')) as `web_view` from `author` as `au` left join `author_affiliation` as `af` on `au`.`author_id` = `af`.`author_id` where `au`.`article_id` = '106808' group by `au`.`author_id` order by `au`.`article_id` asc, `au`.`sequence` asc
      1.56msalphaeurekaselec_live_10_06_2022Author.php#86
      Bindings
      • 0: 106808
      Backtrace
      • 13. app/Models/Author.php:86
      • 14. app/Http/Controllers/ArticleController.php:2533
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select `bo`.* from `bundle_offer` as `bo` where `bo`.`bundle_status` = 'A' order by `bo`.`bundle_id` desc
      260μsalphaeurekaselec_live_10_06_2022BundleOffer.php#57
      Bindings
      • 0: A
      Backtrace
      • 13. app/Models/BundleOffer.php:57
      • 14. app/Http/Controllers/ArticleController.php:2535
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select `subtitle` from `journal` where `continues_publication_journal` = 1
      490μsalphaeurekaselec_live_10_06_2022Article.php#1960
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/Article.php:1960
      • 14. app/Http/Controllers/ArticleController.php:2062
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues, i.issue_id as issue_id,i.title as issue, i.publication_date as issue_pub_date from journal j join volume v on j.journal_id = v.journal_id join issue i on v.volume_id = i.volume_id join article a on a.issue_id = i.issue_id join year y on v.year_id = y.id where j.journal_id = 144 and i.is_uploaded = 1 order by v.volume_name+0 desc, i.title+0 desc limit 1
      34.64msalphaeurekaselec_live_10_06_2022Issue.php#298
      Backtrace
      • 11. app/Models/Issue.php:298
      • 12. app/Http/Controllers/ArticleController.php:2068
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 1 and a.journal_id = 144 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      2.62msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/ArticleController.php:2070
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 4 and a.journal_id = 144 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      2.05msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/ArticleController.php:2071
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select pdf, html, epub, prc from `article_metrics` where `article_id` = 106808 limit 1
      240μsalphaeurekaselec_live_10_06_2022Article.php#744
      Bindings
      • 0: 106808
      Backtrace
      • 14. app/Models/Article.php:744
      • 15. app/Http/Controllers/ArticleController.php:2091
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from content_by_diseases where content_id = 106808 and content_type = 'article' order by status desc limit 1
      300μsalphaeurekaselec_live_10_06_2022Article.php#751
      Backtrace
      • 11. app/Models/Article.php:751
      • 12. app/Http/Controllers/ArticleController.php:2094
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `node_meta` where `nid` = 182157 limit 1
      220μsalphaeurekaselec_live_10_06_2022Meta.php#30
      Bindings
      • 0: 182157
      Backtrace
      • 14. app/Models/Meta.php:30
      • 15. app/Http/Controllers/ArticleController.php:2101
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `bo`.* from `bundle_offer` as `bo` where `bo`.`bundle_status` = 'A' order by `bo`.`bundle_id` desc
      260μsalphaeurekaselec_live_10_06_2022BundleOffer.php#57
      Bindings
      • 0: A
      Backtrace
      • 13. app/Models/BundleOffer.php:57
      • 14. app/Http/Controllers/ArticleController.php:2108
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `tbl_ht_submission` as `h` where `h`.`subtitle` = 'CMIC' and (h.proposal_closing_date = 0 OR TO_DAYS(FROM_UNIXTIME(h.proposal_closing_date)) >= TO_DAYS(NOW())) order by `h`.`manuscript` asc
      350μsalphaeurekaselec_live_10_06_2022Article.php#2025
      Bindings
      • 0: CMIC
      Backtrace
      • 13. app/Models/Article.php:2025
      • 14. app/Http/Controllers/ArticleController.php:2112
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '106808' and content_type = 'a' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      470μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2186
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '10280' and content_type = 'i' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      360μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2207
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '2782' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      350μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2231
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51271243 and j.to_ip >=51271243 )) and ((j.from_date <= 1740514880 and j.to_date >= 1740514880 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2782) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51271243 and j.to_ip >=51271243 )) and ((j.from_date <= 1740514880 and j.to_date >= 1740514880 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2782) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51271243 and j.to_ip >=51271243 )) and ((j.from_date <= 1740514880 and j.to_date >= 1740514880 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2782)
      6.19msalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2272
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51271243 and j.to_ip >=51271243 )) and ((j.from_date <= 1740514880 and j.to_date >= 1740514880 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 10280) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51271243 and j.to_ip >=51271243 )) and ((j.from_date <= 1740514880 and j.to_date >= 1740514880 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 10280) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51271243 and j.to_ip >=51271243 )) and ((j.from_date <= 1740514880 and j.to_date >= 1740514880 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 10280)
      550μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2297
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51271243 and j.to_ip >=51271243 )) and ((j.from_date <= 1740514880 and j.to_date >= 1740514880 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 106808) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51271243 and j.to_ip >=51271243 )) and ((j.from_date <= 1740514880 and j.to_date >= 1740514880 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 106808) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51271243 and j.to_ip >=51271243 )) and ((j.from_date <= 1740514880 and j.to_date >= 1740514880 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 106808)
      530μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2329
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `article` where `first_page` < '207' and is_uploaded = 1 and issue_id = 10280 order by cast(first_page as SIGNED) desc limit 1
      420μsalphaeurekaselec_live_10_06_2022Article.php#1819
      Bindings
      • 0: 207
      Backtrace
      • 14. app/Models/Article.php:1819
      • 15. app/Http/Controllers/ArticleController.php:2470
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `article` where `last_page` > '215' and is_uploaded = 1 and issue_id = 10280 order by cast(first_page as SIGNED) asc limit 1
      370μsalphaeurekaselec_live_10_06_2022Article.php#1831
      Bindings
      • 0: 215
      Backtrace
      • 14. app/Models/Article.php:1831
      • 15. app/Http/Controllers/ArticleController.php:2472
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `language_id` from `multilanguage` where `short_code` = 'en'
      170μsalphaeurekaselec_live_10_06_2022ArticleController.php#2497
      Bindings
      • 0: en
      Backtrace
      • 14. app/Http/Controllers/ArticleController.php:2497
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select `source_lang_label`, `target_lang_label` from `multilanguage_labels` where `target_lang_id` = 1
      210μsalphaeurekaselec_live_10_06_2022MultiLanguage.php#23
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/MultiLanguage.php:23
      • 14. app/Http/Controllers/ArticleController.php:2498
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `id` from `multilanguage_article` where `article_id` = 106808 limit 1
      2.35msalphaeurekaselec_live_10_06_2022ArticleController.php#2506
      Bindings
      • 0: 106808
      Backtrace
      • 16. app/Http/Controllers/ArticleController.php:2506
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 144 and `b`.`banner_from_date` <= 1740514880 and `b`.`banner_to_date` >= 1740514880 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.11msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: J
      • 2: 144
      • 3: 1740514880
      • 4: 1740514880
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 144 and `b`.`banner_from_date` <= 1740514880 and `b`.`banner_to_date` >= 1740514880 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.1msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: J
      • 2: 144
      • 3: 1740514880
      • 4: 1740514880
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='6dce9d045be135b30d1f592fe7b39899'
      210μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\MultiLanguage
    1MultiLanguage.php#?
        _token
        MqDbjJ4dHKQj6oYHYvI8ink6PWzRjCJ6iw29mxki
        uc_cart_id
        6dce9d045be135b30d1f592fe7b39899
        _previous
        array:1 [ "url" => "http://alpha.eurekaselect.com/article/106808" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /article/106808
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:9 [ "cookie" => array:1 [ 0 => "wayfindertarget=eyJpdiI6ImVSZWRyT1gyeE9VbmtSMy8yYzNYbkE9PSIsInZhbHVlIjoiWGVkU3VwVzE2L01CcmJBQW8wb3ZGUldjSW1ZdklIK1gydldZaG5Mdys4Yz0iLCJtYWMiOiIzM2FjNTE5NmJiM2Q2YzFhZTA0ZmM2NjlmNzcyMDE4ZGFkMTEyMzBmNzE4MjExYjg3NmJkZWNiZTAzYzAwNTE0IiwidGFnIjoiIn0%3Dwayfindertarget=eyJpdiI6ImVSZWRyT1gyeE9VbmtSMy8yYzNYbkE9PSIsInZhbHVlIjoiWGVkU3VwVzE2L01CcmJBQW8wb3ZGUldjSW1ZdklIK1gydldZaG5Mdys4Yz0iLCJtYWMiOiIzM2FjNTE5NmJiM2Q2" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] "connection" => array:1 [ 0 => "keep-alive" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] ]
        request_cookies
        0 of 0
        array:1 [ "wayfindertarget" => null ]
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Tue, 25 Feb 2025 20:21:20 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IlFDUUFpNTg0d2swYi9WVlhVV1R0bGc9PSIsInZhbHVlIjoiVitZTTQwTExpNm1JaDF2OUhURXNHZ21SdUl1dFZnYnZ4YnY3V21NTUo1SS84WnhTUjIxTHRmbmVJM2JkNXBGMENnY2VKYm5tcGFhWnE5S0VDaUJlOFA4TTdSK1Rkdk1Nckg2WERjUnFOcis0cGp3aHNsYTAwRlVsS2FobHRRT0kiLCJtYWMiOiIyZWU0NjFhNzkxMGJjMTk5ZTllYTIxYzI1NTQ1YmE3NDBmYzY2MzliYTExOTQ0NGZhMGI2Y2NjMDk1ZGM2MGYwIiwidGFnIjoiIn0%3D; expires=Fri, 28 Feb 2025 08:21:20 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6IlFDUUFpNTg0d2swYi9WVlhVV1R0bGc9PSIsInZhbHVlIjoiVitZTTQwTExpNm1JaDF2OUhURXNHZ21SdUl1dFZnYnZ4YnY3V21NTUo1SS84WnhTUjIxTHRmbmVJM2JkNXBGMENnY2VKY" 1 => "alphaeurekaselectnet_session=eyJpdiI6IkE2RzB0aHAvYXlIdlQxUUgrRWNPV3c9PSIsInZhbHVlIjoiUFRhdnF5bm5FVXU5ZGh1a3UyQWZwYmxmUzFkZUFIRmE2cEZqVWdqdWZ0NjRTamRhMlR2OUVBS1RLSkR5ckk1d3V2UW55eW4rWVpRMnNYZWhQeTNtcW14OENVL0FhUzd2QmJIUkk1U09HMnZycTVmK1RSdnZJOEF5Y000TUg1V0QiLCJtYWMiOiJhMzI2ZjVmNzI2MjcyYTBkYTIyZmZlODRlN2YzZjRiNTg2ODIzMmQ0NzE0YWU5ZDFjMWQ0ZWFkZDE1YTdlMzUyIiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6IkE2RzB0aHAvYXlIdlQxUUgrRWNPV3c9PSIsInZhbHVlIjoiUFRhdnF5bm5FVXU5ZGh1a3UyQWZwYmxmUzFkZUFIRmE2cEZqVWdqdWZ0NjRTamRhMlR2OUVBS1R" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IlFDUUFpNTg0d2swYi9WVlhVV1R0bGc9PSIsInZhbHVlIjoiVitZTTQwTExpNm1JaDF2OUhURXNHZ21SdUl1dFZnYnZ4YnY3V21NTUo1SS84WnhTUjIxTHRmbmVJM2JkNXBGMENnY2VKYm5tcGFhWnE5S0VDaUJlOFA4TTdSK1Rkdk1Nckg2WERjUnFOcis0cGp3aHNsYTAwRlVsS2FobHRRT0kiLCJtYWMiOiIyZWU0NjFhNzkxMGJjMTk5ZTllYTIxYzI1NTQ1YmE3NDBmYzY2MzliYTExOTQ0NGZhMGI2Y2NjMDk1ZGM2MGYwIiwidGFnIjoiIn0%3D; expires=Fri, 28-Feb-2025 08:21:20 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6IlFDUUFpNTg0d2swYi9WVlhVV1R0bGc9PSIsInZhbHVlIjoiVitZTTQwTExpNm1JaDF2OUhURXNHZ21SdUl1dFZnYnZ4YnY3V21NTUo1SS84WnhTUjIxTHRmbmVJM2JkNXBGMENnY2VKY" 1 => "alphaeurekaselectnet_session=eyJpdiI6IkE2RzB0aHAvYXlIdlQxUUgrRWNPV3c9PSIsInZhbHVlIjoiUFRhdnF5bm5FVXU5ZGh1a3UyQWZwYmxmUzFkZUFIRmE2cEZqVWdqdWZ0NjRTamRhMlR2OUVBS1RLSkR5ckk1d3V2UW55eW4rWVpRMnNYZWhQeTNtcW14OENVL0FhUzd2QmJIUkk1U09HMnZycTVmK1RSdnZJOEF5Y000TUg1V0QiLCJtYWMiOiJhMzI2ZjVmNzI2MjcyYTBkYTIyZmZlODRlN2YzZjRiNTg2ODIzMmQ0NzE0YWU5ZDFjMWQ0ZWFkZDE1YTdlMzUyIiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6IkE2RzB0aHAvYXlIdlQxUUgrRWNPV3c9PSIsInZhbHVlIjoiUFRhdnF5bm5FVXU5ZGh1a3UyQWZwYmxmUzFkZUFIRmE2cEZqVWdqdWZ0NjRTamRhMlR2OUVBS1R" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "MqDbjJ4dHKQj6oYHYvI8ink6PWzRjCJ6iw29mxki" "uc_cart_id" => "6dce9d045be135b30d1f592fe7b39899" "_previous" => array:1 [ "url" => "http://alpha.eurekaselect.com/article/106808" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-25 20:21:20GET/article/106808314361