Abstract
The isolation, structure determination and biological evaluation of the eudistomin alkaloids, isolated mainly from marine tunicates of the genus Eudistoma, is described. The compounds are placed in a well defined unique structural class based upon biogenic considerations. The methods which have been employed towards total synthesis of these metabolites are reviewed in detail.
Keywords: Eudistomin marine alkaloids, Marine tunicates, Eudistoma, Marine natural products, Anticancer, Antibacterial, Antiviral activities, Dolabella, Auricularia, Bugula neritina, Ecteinascidia, Cancer, Lissoclinum fragile, Pseudodistoma aureum, Synthesis, Cysteine derived, Eudistomins, Eudistomidins, Glutamate, Proline derived, Beta carbolines
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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