Login Register Cart 0
Generic placeholder image

Current Bioactive Compounds

Editor-in-Chief

ISSN (Print): 1573-4072
ISSN (Online): 1875-6646

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

Evaluation of the Antioxidant and Antimicrobial Activity of Ziziphora clinopodiodes Essential Oil Eluted at Different Times

Author(s): Mojgan Alizadeh, Akram Arianfar* and Ameneh Mohammadi

Volume 17, Issue 3, 2021

Published on: 07 May, 2020

Page: [256 - 260] Pages: 5

DOI: 10.2174/1573407216999200507122039

Price: $65

Abstract

Objective: Ziziphora clinopodioides is an edible medicinal plant belonging to the Labiatae family that is widespread all over Iran. It used in culinary and also in cold and cough treatments in Iran. The aim of the present work was to evaluate the effect of different timeframes during hydrodistillation on essential oil composition, antimicrobial and antioxidant activity.

Materials and Methods: The essential oil of Z. clinopodiodes was extracted via hydrodistillation with Clevenger apparatus. The fractions of essential oil were captured at 6 times from the beginning of the distillation: (10, 20, 60, 120, 180 and 240 min). The fractions of essential oil were analyzed by GC/MS and their antibacterial, antifungal and antioxidant activities were studied by Disk - well diffusion and DPPH methods, respectively.

Results: Six distillation times and whole essential oil were captured during hydrodistillation. Essential oil yield dropped off significantly during distillation progressed (1.0% for 10 min and 0.025 for 240 min). 1,8 Cineol, Isomenthone, Pulegone, Piperitenone and Citronellic acid were major compounds in fractions and they were affected by distillation times. Pulegone was a major compound in all of the essential oils. In antioxidant activity assay, whole essential oil was stronger than positive control and fractions of essential oil, because of higher levels of Isomenthone, Piperitenone and Citronellic acid. Strongest antimicrobial activity against S. aureus, E. coli and C. albicans was observed from 10 min fraction.

Conclusion: Our results indicated that distillation time can create essential oils with specific properties and we can achieve more efficient essential oil in short times.

Keywords: Ziziphora clinopodioides, fractions of essential oil, different timeframes, antioxidant, antimicrobial, distillation.

Graphical Abstract

[1]
Rechinger, K.H. Flora iranica: Akademische Druck-u; Verlagsanstalt: Graz, Austria, 1982.
[2]
Zargari, A. Iranian medicinal plants; Tehran University Press: Tehran, 1995.
[3]
Salehi, P.; Sonboli, A.; Eftekhar, F.; Nejad-Ebrahimi, S.; Yousefzadi, M. Essential oil composition, antibacterial and antioxidant activity of the oil and various extracts of Ziziphora clinopodioides subsp. rigida (BOISS.) RECH. f. from Iran. Biol. Pharm. Bull., 2005, 28(10), 1892-1896.
[http://dx.doi.org/10.1248/bpb.28.1892] [PMID: 16204941]
[4]
Sonboli, A.; Mirjalili, M.H.; Hadian, J.; Ebrahimi, S.N.; Yousefzadi, M. Antibacterial activity and composition of the essential oil of Ziziphora clinopodioides subsp. bungeana (Juz.) Rech. f. from Iran. Z. Natforsch. C J. Biosci., 2006, 61(9-10), 677-680.
[http://dx.doi.org/10.1515/znc-2006-9-1011] [PMID: 17137113]
[5]
Burt, S. Essential oils: Their antibacterial properties and potential applications in foods-A review. Int. J. Food Microbiol., 2004, 94(3), 223-253.
[http://dx.doi.org/10.1016/j.ijfoodmicro.2004.03.022] [PMID: 15246235]
[6]
Zheljazkov, V.D.; Pickett, K.M.; Caldwell, C.D.; Pincock, J.A.; Roberts, J.C.; Mapplebeck, L. Cultivar and sowing date effects on seed yield and oil composition of coriander in atlantic Canada. Ind Crop Prod, 2008, 28(1), 88-94.
[http://dx.doi.org/10.1016/j.indcrop.2008.01.011]
[7]
Sintim, H.Y.; Burkhardt, A.; Gawde, A.; Cantrell, C.L.; Astatkie, T.; Obour, A.E. Hydrodistillation time affects dill seed essential oil yield, composition, and bioactivity. Ind. Crop. Prod., 2015, 63, 190-196.
[http://dx.doi.org/10.1016/j.indcrop.2014.09.058]
[8]
Zheljazkov, V.D.; Astatkie, T.; Jeliazkova, E.A.; Schlegel, V. Distillation time alters essential oil yield, composition, and antioxidant activity of male Juniperus scopulorum trees. J. Oleo Sci., 2012, 61(10), 537-546.
[http://dx.doi.org/10.5650/jos.61.537] [PMID: 23018851]
[9]
Burkhardt, A.; Sintim, H.Y.; Gawde, A.; Cantrell, C.L.; Astatkie, T.; Zheljazkov, V.D. Method for attaining fennel (Foeniculum vulgare mill.) seed oil fractions with different composition and antioxidant capacity. J. Appl. Res. Med. Aromat. Plants, 2015, 2(3), 87-91.
[http://dx.doi.org/10.1016/j.jarmap.2015.04.003]
[10]
Cannon, J.B.; Cantrell, C.L.; Astatkie, T.; Zheljazkov, V.D. Modification of yield and composition of essential oils by distillation time. Ind. Crop Prod., 2013, 41, 214-220.
[http://dx.doi.org/10.1016/j.indcrop.2012.04.021]
[11]
Mohammadi, A.; Arianfar, A.; Noori, M. Chemical composition, antioxidant and antibacterial activity of Artemisia diffusa essential oil. J. Essent. Oil Bear. Plants, 2017, 20(5), 1235-1243.
[http://dx.doi.org/10.1080/0972060X.2017.1345329]
[12]
Moghaddam, P.Z.; Mohammadi, A.; Feyzi, P.; Alesheikh, P. In vitro antioxidant and antibacterial activity of various extracts from exocarps and endocarps of walnut. Pak. J. Pharm. Sci., 2017, 30(5), 1725-1731.
[PMID: 29084695]
[13]
Dahmer, J.; do Carmo, G.; Mostardeiro, M.A.; Neto, A.T.; da Silva, U.F.; Dalcol, I.I.; Morel, A.F. Antibacterial activity of Discaria americana Gillies ex Hook (Rhamnaceae). J. Ethnopharmacol., 2019, 239, 111635.
[http://dx.doi.org/10.1016/j.jep.2018.12.009] [PMID: 30543915]
[14]
Kamali, H.; Sani, T.A.; Mohammadi, A.; Alesheikh, P.; Khodaverdi, E.; Hadizadeh, F. A comparison between pressurized hot water and pressurized liquid extraction for optimizing phenolic and antioxidants capacity of the wooden layer between of walnut seed. J Supercrit. Fluid, 2018, 133, 535-541.
[http://dx.doi.org/10.1016/j.supflu.2017.10.017]
[15]
Zheljazkov, V.D.; Semerdjieva, I.B.; Dincheva, I.; Kacaniova, M.; Astatkie, T.; Radoukova, T. Antimicrobial and antioxidant activity of Juniper galbuli essential oil constituents eluted at different times. Ind. Crop Prod., 2017, 109, 529-537.
[http://dx.doi.org/10.1016/j.indcrop.2017.08.057]
[16]
Dembistikii, A.; Bergalier, E.; Kyazimer, I. Morphological and phytochemical study of Ziziphora tenuior l. Chem. Nat. Compd., 1995, 31, 673-675.
[17]
Sezik, E.; Tümen, G.; Başer, K. Ziziphora tenuior l., a new source of pulegone. Flavour Fragrance J., 1991, 6(1), 101-103.
[http://dx.doi.org/10.1002/ffj.2730060116]
[18]
Zheljazkov, V.D; Shiwakoti, S.; Astatkie, T.; Salamon, I.; Grul’ová, D.; Mudrencekova, S. ‎Yield, composition, and antioxidant capacity of ground cumin seed oil fractions obtained at ‎different time points during the hydrodistillation. Hort. Sci., 2015, 50(8), 1213-1217.
[http://dx.doi.org/10.21273/HORTSCI.50.8.1213]
[19]
Kim, H.J.; Chen, F.; Wu, C.; Wang, X.; Chung, H.Y.; Jin, Z. Evaluation of antioxidant activity of Australian tea tree (Melaleuca alternifolia) oil and its components. J. Agric. Food Chem., 2004, 52(10), 2849-2854.
[http://dx.doi.org/10.1021/jf035377d] [PMID: 15137824]
[20]
Mimica-Dukić, N.; Božin, B.; Soković, M.; Mihajlović, B.; Matavulj, M. Antimicrobial and antioxidant activities of three Mentha species essential oils. Planta Med., 2003, 69(5), 413-419.
[http://dx.doi.org/10.1055/s-2003-39704] [PMID: 12802721]
[21]
Jassbi, A.R.; Mirzaie, Y.; Firuzi, O.; Asadollahi, M. Composition and cytotoxic activity of the essential oils of Mentha mozaffarianii jamzad at different phenological stages. Curr. Bioact. Compd., 2018, 14(2), 191-196.
[http://dx.doi.org/10.2174/1573407213666170201114502]
[22]
Duru, M.E.; Oztürk, M.; Uğur, A.; Ceylan, O. The constituents of essential oil and in vitro antimicrobial activity of Micromeria cilicica from Turkey. J. Ethnopharmacol., 2004, 94(1), 43-48.
[http://dx.doi.org/10.1016/j.jep.2004.03.053] [PMID: 15261961]
[23]
Shakeri, A.; Sharifi, M.J.; Fazly Bazzaz, B.S.; Emami, A.; Soheili, V.; Sahebkar, A.; Asili, J. Bioautography detection of antimicrobial compounds from the essential oil of Salvia pachystachys. Curr. Bioact. Compd., 2018, 14(1), 80-85.
[http://dx.doi.org/10.2174/1573407212666161014132503]

Rights & Permissions Print Cite
Article Metrics
4
© 2024 Bentham Science Publishers | Privacy Policy