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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

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Editorial

Modulation of Kinases by Small Molecules for Therapeutic Management of Various Diseases - Part I

Author(s): Sandip B. Bharate

Volume 20, Issue 12, 2020

Page: [1057 - 1058] Pages: 2

DOI: 10.2174/156802662012200504090532

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Fry, D.W.; Kraker, A.J.; McMichael, A.; Ambroso, L.A.; Nelson, J.M.; Leopold, W.R.; Connors, R.W.; Bridges, A.J. A specific inhibitor of the epidermal growth factor receptor tyrosine kinase. Science, 1994, 265, 1093-1095.
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Dar, A.C.; Shokat, K.M. The evolution of protein kinase inhibitors from antagonists to agonists of cellular signaling. Annu. Rev. Biochem., 2011, 80, 769-795.
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TurabNaqvi, A.A.; Hasan, G.M.; Hassan, M.I. Targeting tau hyperphosphorylation via kinase inhibition- Strategy to address Alzheimers’ disease. Curr. Top. Med. Chem., 2020, 20(12), 1059-1073.
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Bheemanaboina, R.R.Y. Isoform-Selective PI3K Inhibitors for Various Diseases. Curr. Top. Med. Chem., 2020, 20(12), 1074-1092.
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Gill, M.S.A.; Saleem, H.; Ahemad, N. Plant extracts and their secondary metabolites as modulators of kinases. Curr. Top. Med. Chem., 2020, 20(12), 1093-1104.
[8]
Kumar, M.; Joshi, G.; Chatterjee, J.; Kumar, R. Epidermal Growth Factor Receptor and its trafficking regulation by acetylation: Implication in resistance and exploring the newer therapeutic avenues in cancer. Curr. Top. Med. Chem., 2020, 20(12), 1105-1123.
[9]
Bharate, S.B.; Sawant, S.D.; Singh, P.P.; Vishwakarma, R.A. Kinase inhibitors of marine origin. Chem. Rev., 2013, 113, 6761-6815.
[10]
Raghuvanshi, R.; Bharate, S.B. Preclinical and clinical studies on bryostatins, a class of marine-derived protein kinase C modulators: A mini-review. Curr. Top. Med. Chem., 2020, 20(12), 1124-1135.

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