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General Review Article

基于miRNA生物标志物系统发育分析的抑郁与胃食管反流之间的关联

卷 27, 期 38, 2020

页: [6536 - 6547] 页: 12

弟呕挨: 10.2174/0929867327666200425214906

价格: $65

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摘要

许多临床研究表明，重度抑郁症（MD）与胃食管反流病（GERD）之间存在关联。 两种疾病均显示影响很大一部分全球人口。 了解这两种疾病合并症机制的更高级研究可以为开发这两种疾病的新疗法提供启示。 据我们所知，文献中还没有任何研究使用其miRNA生物标记物研究MD和GERD之间的关系。 我们采用系统发育分析来分析其miRNA生物标记。 根据我们的分析结果，可以通过miRNA系统发育探索这两种疾病之间的关联。 除了来自系统发育分析的证据外，我们还基于台湾生物库数据证明了MD和GERD之间关系的流行病学证据。

关键词: 严重抑郁症，胃食管反流，microRNA，系统发育分析，MD，GERD，常见消化系统疾病。

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