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SARS-CoV-2：最近基于洛匹那韦/利托那韦/达鲁那韦/米米诺韦，羟氯喹，瑞德西韦，法维吡拉韦和其他药物治疗新冠状病毒的抗病毒疗法的报道

卷 27, 期 27, 2020

页: [4536 - 4541] 页: 6

弟呕挨: 10.2174/0929867327666200416131117

摘要

在此，我们报道了成功用于治疗SARS-CoV-2冠状病毒(又称COVID-19冠状病毒)的实验药物的最新进展。特别是，有报道称，洛匹那韦/利托那韦[广泛用于治疗人类免疫缺陷病毒(HIV)感染]与抗流感药物奥司他韦联合治疗后，有几例患者康复。此外，瑞德西韦以前曾用于埃博拉病毒患者，在美国也被证明对冠状病毒有效，而抗疟氯喹和羟氯喹、法维吡拉韦以及联合用药达鲁那韦和米米诺韦(在患者治疗中)最近也被记录为具有抗SARS-CoV-2的效果。由于过去几周的康复/死亡比率显著上升，特别是在中国，因此很明显，实验性抗病毒治疗、医院重症监护病房的可用性以及政府严格的控制措施，在应对这一病毒方面都发挥了重要作用。这也强调了科学界迫切需要致力于开发其他更具体的抗病毒策略。

关键词: SARS-CoV-2，冠状病毒，COVID-19，抗病毒药，羟氯喹，瑞德西韦，法维吡拉韦，洛匹那韦，利托那韦。

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