Chromatography-Free Synthesis of 1,2,4-Oxadiazoles Using ROMPGEL-Supported Acylating Reagents

Title: Chromatography-Free Synthesis of 1,2,4-Oxadiazoles Using ROMPGEL-Supported Acylating Reagents

Volume: 3 Issue: 2

Author(s): A. G.M. Barrett, S. M. Cramp, R. S. Roberts and F. J. Zecri

Affiliation:

Keywords: Chromatography free synthesis, Acylating reagents, 1,2,4 oxadiazoles, Ring opening metathesis polymer, Polymers ROMPGELs

Abstract: 1,2,4-Oxadiazoles were synthesized in solution from aromatic amidoximes and acylating agents supported on a ring opening metathesis polymer (ROMPGEL) backbone. High yields and purities of the 1,2,4-oxadiazoles were obtained with minimal purification.

Cite this article as:

Barrett G.M. A., Cramp M. S., Roberts S. R. and Zecri J. F., Chromatography-Free Synthesis of 1,2,4-Oxadiazoles Using ROMPGEL-Supported Acylating Reagents, Combinatorial Chemistry & High Throughput Screening 2000; 3 (2) . https://dx.doi.org/10.2174/1386207003331733

DOI https://dx.doi.org/10.2174/1386207003331733	Print ISSN 1386-2073
Publisher Name Bentham Science Publisher	Online ISSN 1875-5402