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Current Protein & Peptide Science

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ISSN (Print): 1389-2037
ISSN (Online): 1875-5550

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Review Article

GRASP55: A Multifunctional Protein

Author(s): Hongrong Wu, Tianjiao Li and Jianfeng Zhao*

Volume 21, Issue 6, 2020

Page: [544 - 552] Pages: 9

DOI: 10.2174/1389203721666200218105302

Price: $65

Abstract

GRASP55 was first found as Golgi cisternae stacking protein. Due to the crucial role of Golgi in vesicular trafficking and protein modification, GRASP55 was found to function in these two aspects. Further investigation revealed that GRASP55 also participates in the unconventional secretory pathway under stress. Moreover, GRASP55 is involved in autophagy initiation and autophagosome maturation, as well as cell activity.

Keywords: GRASP55, Golgi, Autophagy, Unconventional secretory pathway, Vesicular trafficking, Golgin45.

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