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Current Bioactive Compounds

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ISSN (Print): 1573-4072
ISSN (Online): 1875-6646

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Research Article

The Influence of Heating and Photosensitization on the Stability of Lutein- Loaded Lipid-Core Nanocapsules

Author(s): Aelson A.S. Brum, Médelin M. da Silva, Priscilla P. dos Santos, Allana V.S. Brasil, Karina Paese, Silvia S. Guterres, Simone H. Flôres and Alessandro de O. Rios*

Volume 16, Issue 9, 2020

Page: [1340 - 1345] Pages: 6

DOI: 10.2174/1573407216666200211094654

Price: $65

Abstract

Background: Despite lutein is unstable in light, heat, and oxygen, it is a good quencher of singlet oxygen. The present study evaluated the stability of lutein (92% of purity) in Lipid-core Nanocapsules (Lutein-LNC) prepared through interfacial deposition of preformed polymer, during photosensitization (5-25°C) and heating (70-90°C).

Methods: The Lutein-LNC was characterized and presented a polydispersity index of 0.11, an average diameter of 191 nm (dynamic light scattering), zeta potential of -9.14 mV and entrapment efficiency of 100%.

Results and Discussion: During photosensitization and heating, Lutein-LNC exhibited activation Energy (Ea) of 24.67 kcal/mol and 9.96 kcal/mol, respectively, and these values of Lutein-LNC were higher than free lutein values, reported in other studies for both experiments.

Conclusion: The results obtained in this study suggested that nanotechnology can improve the stability of lutein for future applications in the food industry.

Keywords: Heating, lutein, photodegradation, sensitizer, stability, zeaxanthin.

Graphical Abstract

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