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Current Bioactive Compounds

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Mini-Review Article

A Mini Review on Recent Advancements in the Therapeutic Potentials of Benzothiazoles

Author(s): Rubina Bhutani*, Garima Kapoor, Dharam P. Pathak, Asif Husain, Ravi Kant and Ruhi Ali

Volume 17, Issue 1, 2021

Published on: 23 December, 2019

Page: [4 - 27] Pages: 24

DOI: 10.2174/1573407216666191223093550

Price: $65

Abstract

Among the various fused heterocyclic rings, benzothiazole and its analogs have been explored broadly in search of newer therapeutic medicinal agents. The benzothiazole scaffold has been associated with huge biological potential like anticancer, antidiabetic, anti-inflammatory, antitubercular, antiviral, anti-convulsant etc. The occurrence of benzothiazole core in various compounds proves its value in the sphere of pharmaceutical chemistry. The connected research and developments in benzothiazole based chemistry become an active topic for medicinal scientists. A large number of benzothiazole and its heterocyclic derivatives are available in the market and used for the treatment as clinical drugs have been extensively used in practice to treat diverse types of ailments with high therapeutic potential. This review presents the latest therapeutic developments of benzothiazole containing compounds in the medicinal chemistry.

Keywords: Anti-diabetic, anti-inflammatory, anti-viral, benzothiazole, biological potential, fused heterocycle.

Graphical Abstract

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