Abstract
Aims and Objective: An efficient and practical procedure for the synthesis of heterocyclic compounds such as quinazolines, quinoxalines and bis(indolyl)methanes was developed using 3,5-bis(trifluoromethyl) phenyl ammonium hexafluorophosphate (BFPHP) as a novel organocatalyst.
Materials and Methods: All of the obtained products are known compounds and identified by IR, 1HNMR, 13CNMR and melting points.
Result: Various products were obtained in good to excellent yields under reaction conditions.
Conclusion: The BFPHP organocatalyst demonstrates a novel class of non-asymmetric organocatalysts, which has gained much attention in green chemistry.
Keywords: Organocatalyst, green chemistry, quinazoline, multicomponent, heterocyclic, anticancer.
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