Login Register Cart 0
Generic placeholder image

Current Women`s Health Reviews

Editor-in-Chief

ISSN (Print): 1573-4048
ISSN (Online): 1875-6581

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

The Consumption of Folic Acid During Preconception Period and its Related Knowledge among Iranian Women

Author(s): Roghieh Bayrami, Alireza Didarloo and Afsaneh Asadinejad*

Volume 16, Issue 1, 2020

Page: [33 - 38] Pages: 6

DOI: 10.2174/1573404815666191025100525

Price: $65

Abstract

Background: The use of folic acid in the preconception stage can prevent neural tube defects if taken at the right time.

Objective: The purpose of this study was to investigate the intake of folic acid in the preconception period and its related knowledge among Iranian women.

Materials and Methods: In this cross-sectional study, 230 married women who had decided to become pregnant were selected from health centers using the multistage cluster sampling method in Urmia-Iran, in 2018. The data collection tool was a self-structured, valid, reliable questionnaire consisting of the following parts: women’s demographic data, use of folic acid, and knowledge regarding the use of folic acid and its related benefits. Data analysis was carried out using SPSS v21 software. A P value < 0.05 was considered statistically significant.

Results: In this study, the mean age of the participants was 30.73±6.77 years. About 49 (21.3%) women used folic acid supplements in the correct way. The mean score of women's knowledge was 6.20 ± 2.15. The minimum and maximum scores for knowledge were 1-10. There was a statistically significant relationship between taking folic acid with the subject's knowledge about folic acid (p=0.035), family income (p=0.027), women's job (p=0.046), education level (p=0.001) and the number of children (p=0.026).

Conclusion: The study revealed that the status of taking folic acid among women and their knowledge concerning folic acid and its related importance were not satisfactory. This finding suggests that there is a need to give emphasis and deliver health education about preconception folic acid supplementation for women.

Keywords: Folic acid, knowledge, preconception period, women, neural tube defect, Iranian women.

Graphical Abstract

[1]
Gaskins AJ, Toth TL, Chavarro JE. Prepregnancy nutrition and early pregnancy outcomes. Curr Nutr Rep 2015; 4(3): 265-72.
[http://dx.doi.org/10.1007/s13668-015-0127-5] [PMID: 26457232]
[2]
Khoshnood B, Loane M, de Walle H, et al. Long term trends in prevalence of neural tube defects in Europe: population based study. BMJ 2015; 351: h5949.
[http://dx.doi.org/10.1136/bmj.h5949] [PMID: 26601850]
[3]
Chen C, Ke J, Zhou XE, et al. Structural basis for molecular recognition of folic acid by folate receptors. Nature 2013; 500(7463): 486-9.
[http://dx.doi.org/10.1038/nature12327] [PMID: 23851396]
[4]
Czeizel AE. Prevention of congenital abnormalities by periconceptional multivitamin supplementation. BMJ 1993; 306(6893): 1645-8.
[http://dx.doi.org/10.1136/bmj.306.6893.1645] [PMID: 8324432]
[5]
Morris JK, Rankin J, Draper ES, et al. Prevention of neural tube defects in the UK: a missed opportunity. Arch Dis Child 2016; 101(7): 604-7.
[http://dx.doi.org/10.1136/archdischild-2015-309226] [PMID: 26681697]
[6]
Tobias DK, Zhang C, Chavarro J, et al. Prepregnancy adherence to dietary patterns and lower risk of gestational diabetes mellitus. Am J Clin Nutr 2012; 96(2): 289-95.
[http://dx.doi.org/10.3945/ajcn.111.028266] [PMID: 22760563]
[7]
Viswanathan M, Treiman KA, Kish-Doto J, Middleton JC, Coker-Schwimmer EJ, Nicholson WK. Folic acid supplementation for the prevention of neural tube defects: an updated evidence report and systematic review for the US Preventive Services Task Force. JAMA 2017; 317(2): 190-203.
[http://dx.doi.org/10.1001/jama.2016.19193] [PMID: 28097361]
[8]
Eichholzer M, Tönz O, Zimmermann R. Folic acid: a public-health challenge. Lancet 2006; 367(9519): 1352-61.
[http://dx.doi.org/10.1016/S0140-6736(06)68582-6] [PMID: 16631914]
[9]
Rofail D, Colligs A, Abetz L, Lindemann M, Maguire L. Factors contributing to the success of folic acid public health campaigns. J Public Health (Oxf) 2012; 34(1): 90-9.
[http://dx.doi.org/10.1093/pubmed/fdr048] [PMID: 21727078]
[10]
Stevens GA, Finucane MM, De-Regil LM, et al. Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995-2011: a systematic analysis of population-representative data. Lancet Glob Health 2013; 1(1): e16-25.
[http://dx.doi.org/10.1016/S2214-109X(13)70001-9] [PMID: 25103581]
[11]
Roudsari RL, Bayrami R, Javadnoori M, Allahverdipour H, Esmaily H. Patterns and determinants of preconception health behaviors in Iranian women. Iran Red Crescent Med J 2016; 18(12)e59044
[12]
Ghaffari Sardasht F, Keramat A, Irani M. The level of Knowledge and consumption of Folic Acid in pregnancy and pre-conception: A Systematic Review and Meta-analysis. Iran J Obs Gynecol Infertil 2019; 22(2): 84-95.
[13]
Shulman HB, Gilbert BC, Msphbrenda CG, Lansky A. The Pregnancy Risk Assessment Monitoring System (PRAMS): current methods and evaluation of 2001 response rates. Public Health Rep 2006; 121(1): 74-83.
[http://dx.doi.org/10.1177/003335490612100114] [PMID: 16416701]
[14]
Lawshe CA. Quantitative Approach to Content Validity. Person Psychol 1975; 28: 563-75.
[http://dx.doi.org/10.1111/j.1744-6570.1975.tb01393.x]
[15]
Lawal TA, Adeleye AO. Determinants of folic acid intake during preconception and in early pregnancy by mothers in Ibadan, Nigeria. Pan Afr Med J 2014; 19: 113.
[http://dx.doi.org/10.11604/pamj.2014.19.113.4448] [PMID: 25722786]
[16]
Bestwick JP, Huttly WJ, Morris JK, Wald NJ. Prevention of neural tube defects: a cross-sectional study of the uptake of folic acid supplementation in nearly half a million women. PLoS One 2014; 9(2)e89354
[http://dx.doi.org/10.1371/journal.pone.0089354] [PMID: 24586711]
[17]
Dessie MA, Zeleke EG, Workie SB, Berihun AW. Folic acid usage and associated factors in the prevention of neural tube defects among pregnant women in Ethiopia: cross-sectional study. BMC Pregnancy Childbirth 2017; 17(1): 313.
[http://dx.doi.org/10.1186/s12884-017-1506-2] [PMID: 28934941]
[18]
Bille C, Murray JC, Olsen SF. Folic acid and birth malformations. BMJ 2007; 334(7591): 433-4.
[http://dx.doi.org/10.1136/bmj.39133.386296.BE] [PMID: 17332537]
[19]
Amitai Y, Fisher N, Haringman M, Meiraz H, Baram N, Leventhal A. Increased awareness, knowledge and utilization of preconceptional folic acid in Israel following a national campaign. Prev Med 2004; 39(4): 731-7.
[http://dx.doi.org/10.1016/j.ypmed.2004.02.042] [PMID: 15351539]
[20]
Kim J, Yon M, Kim CI, et al. Preconceptional use of folic acid and knowledge about folic acid among low-income pregnant women in Korea. Nutr Res Pract 2017; 11(3): 240-6.
[http://dx.doi.org/10.4162/nrp.2017.11.3.240] [PMID: 28584581]
[21]
Kondo A, Morota N, Date H, et al. Awareness of folic acid use increases its consumption, and reduces the risk of spina bifida. Br J Nutr 2015; 114(1): 84-90.
[http://dx.doi.org/10.1017/S0007114515001439] [PMID: 25999131]
[22]
Bener A, Al Maadid MG, Al-Bast DA, Al-Marri S. Maternal knowledge, attitude and practice on folic acid intake among Arabian Qatari women. Reprod Toxicol 2006; 21(1): 21-5.
[http://dx.doi.org/10.1016/j.reprotox.2005.07.004] [PMID: 16112540]
[23]
Ren A, Zhang L, Li Z, Hao L, Tian Y, Li Z. Awareness and use of folic acid, and blood folate concentrations among pregnant women in northern China--an area with a high prevalence of neural tube defects. Reprod Toxicol 2006; 22(3): 431-6.
[http://dx.doi.org/10.1016/j.reprotox.2006.02.003] [PMID: 16549319]
[24]
Nawapun K, Phupong V. Awareness of the benefits of folic acid and prevalence of the use of folic acid supplements to prevent neural tube defects among Thai women. Arch Gynecol Obstet 2007; 276(1): 53-7.
[http://dx.doi.org/10.1007/s00404-006-0305-1] [PMID: 17186253]
[25]
Goshu YA, Liyeh TM, Ayele AS, Zeleke LB, Kassie YT. Women’s awareness and associated factors on preconception folic acid supplementation in Adet, northwestern Ethiopia, 2016: implication of reproductive health. J Nutr Metab 2018; 2018: 4936080.
[http://dx.doi.org/10.1155/2018/4936080] [PMID: 30116639]
[26]
Temel S, Erdem Ö, Voorham TA, Bonsel GJ, Steegers EA, Denktaş S. Knowledge on preconceptional folic acid supplementation and intention to seek for preconception care among men and women in an urban city: a population-based cross-sectional study. BMC Pregnancy Childbirth 2015; 15(1): 340.
[http://dx.doi.org/10.1186/s12884-015-0774-y] [PMID: 26684337]
[27]
Lian H, Ma D, Zhou SF, Li X. Knowledge and use of folic acid for birth defect prevention among women of childbearing age in Shanghai, China: a prospective cross-sectional study. Med Sci Monit 2011; 17(12): PH87-92.
[http://dx.doi.org/10.12659/MSM.882111] [PMID: 22129911]
[28]
Bhide P, Kar A. Prevalence and determinants of folate deficiency among urban Indian women in the periconception period. Eur J Clin Nutr 2019; 73(12): 1639-41.
[http://dx.doi.org/10.1038/s41430-018-0255-2] [PMID: 30026502]
[29]
Alreshidi FF, Almujil AS, Malak AS. Awareness of folic acid use among Saudi women attending outpatient clinics at King Fahad Medical City. J Family Med Prim Care 2018; 7(5): 957-62.
[PMID: 30598940]

Rights & Permissions Print Cite
Article Metrics
13
3
1
1
© 2024 Bentham Science Publishers | Privacy Policy