Abstract
A simple and environmentally benign room temperature synthesis of 1,2,4-triazolidine-3- thiones is described using Envirocat EPZ-10R as a solid acid catalyst in the aqueous medium. The use of Envirocat EPZ-10R as a green catalyst, reusability of the catalyst, water as a universal solvent and good yields of the product are the attractive features of the present method.
Keywords: Clay, 1, 2, 4-triazolidine-3-thiones, envirocat EPZ-10R, thiosemicarbazide, water, reusability.
Graphical Abstract
[http://dx.doi.org/10.1016/j.crci.2011.08.002]
[http://dx.doi.org/10.1016/S0040-4039(00)73698-7]
[http://dx.doi.org/10.1016/j.cattod.2008.04.004]
[http://dx.doi.org/10.5012/bkcs.2004.25.12.1929]
[http://dx.doi.org/10.1039/a905811g]
[http://dx.doi.org/10.1007/PL00010311]
[http://dx.doi.org/10.1080/00397910903221027]
[http://dx.doi.org/10.1016/S0960-894X(00)00422-4] [PMID: 10999482]
[http://dx.doi.org/10.1002/jhet.5570170547]
[http://dx.doi.org/10.1021/jm00396a003] [PMID: 3336031]
[http://dx.doi.org/10.1135/cccc19932211]
[http://dx.doi.org/10.1007/BF02331857]
[http://dx.doi.org/10.1002/slct.201600348]
[PMID: 15610621]
[http://dx.doi.org/10.1002/jccs.200700012]
[http://dx.doi.org/10.1016/j.tetlet.2012.07.054]
[http://dx.doi.org/10.1016/j.bmc.2007.06.006] [PMID: 17587585]
[http://dx.doi.org/10.1039/c3ra46916f]
[http://dx.doi.org/10.1039/c3ra44641g]
[http://dx.doi.org/10.1007/s11164-015-2267-z]
[http://dx.doi.org/10.1016/j.tetlet.2014.10.052]
[http://dx.doi.org/10.1080/00397911.2016.1263338]
[http://dx.doi.org/10.1016/j.jfluchem.2017.01.012]