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Current Drug Safety

Editor-in-Chief

ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

Research Article

Impact of Abuse of Topical Corticosteroids and Counterfeit Cosmetic Products for the Face: Prospective Demographic Study in Basrah City, Iraq

Author(s): Ausama Ayob Jaccob*, Abdulla Ayob Yaqoub and Muataz Abdulla Rahmani

Volume 15, Issue 1, 2020

Page: [25 - 31] Pages: 7

DOI: 10.2174/1574886314666191001100357

Abstract

Background: Topical corticosteroids are highly effective compounds that are now widely used in dermatology for the treatment of various autoimmune and inflammatory disorders. Many corticosteroids are misused for diverse indications such as pigmentation, acne, pruritus, fungal or bacterial infections, rashes, and numerous other conditions. These products contain various constituents, most of which have hazards or toxic elements.

Objective: The aim is to raise awareness among individuals in the city of Basrah, Iraq about the uses and abuses of applying fake products to the face to inform the consumers about potential harmful adverse effects.

Methods: This study was a prospective multi-center clinic questionnaire of a demographic that involved the outpatient dermatology departments at the Al-Basrah teaching hospital and the Abu Al-Khaseeb hospital as well as the private clinics of two dermatology specialists in Basrah. A total of 235 patients with facial dermatoses secondary to the application of topical corticosteroids and counterfeit products or, a mixed formulation, for cosmetic purposes were recruited.

Results: Most enrolled patients were female with 10-20 years aged group. The majority applied these products due to friends or pharmacy encouragement. Motivations for the use of these products included: skin fairness, lightening, and general cosmetic. Interestingly, acne and erythema were common whilst, atrophy, dryness, telangiectasia, and hirsutism appear on long- term use only.

Conclusion: The abuse of counterfeit cosmetic products and topical corticosteroids is in progress and they have adverse health events. There are many causes behind the abuse but the lack of education, lack of restriction, profitable for sellers and low prices are the main.

Keywords: Topical corticosteroids, counterfeit cosmetic products, inflammatory disorders, pigmentation, acne, pruritus.

Graphical Abstract

[1]
Schoepe S, Schäcke H, May E, Asadullah K. Glucocorticoid therapy-induced skin atrophy. Exp Dermatol 2006; 15(6): 406-20.
[http://dx.doi.org/10.1111/j.0906-6705.2006.00435.x] [PMID: 16689857]
[2]
Nagesh TS, Akhilesh A. Topical steroid awareness and abuse: A prospective study among dermatology outpatients. Indian J Dermatol 2016; 61(6): 618-21.
[http://dx.doi.org/10.4103/0019-5154.193666] [PMID: 27904178]
[3]
Hengge UR, Ruzicka T, Schwartz RA, Cork MJ. Adverse effects of topical glucocorticosteroids. J Am Acad Dermatol 2006; 54(1): 1-15.
[http://dx.doi.org/10.1016/j.jaad.2005.01.010] [PMID: 16384751]
[4]
Mehta AB, Nadkarni NJ, Patil SP, Godse KV, Gautam M, Agarwal S. Topical corticosteroids in dermatology. Indian J Dermatol Venereol Leprol 2016; 82(4): 371-8.
[http://dx.doi.org/10.4103/0378-6323.178903] [PMID: 27279294]
[5]
Lahiri K, Coondoo A. Topical steroid damaged/dependent face (TSDF): An entity of cutaneous pharmacodependence. Indian J Dermatol 2016; 61(3): 265-72.
[http://dx.doi.org/10.4103/0019-5154.182417] [PMID: 27293246]
[6]
Pal D, Biswas P, Das S, De A, Sharma N, Ansari A. Topical steroid damaged/dependent face (TSDF): A study from a tertiary care hospital in Eastern India. Indian J Dermatol 2018; 63(5): 375-9.
[http://dx.doi.org/10.4103/ijd.IJD_218_17] [PMID: 30210157]
[7]
Sahib MN. Screening of two glucocorticoids in non-prescription skin whitening creams purchased via internet in Iraq by HPLC method. J Appl Pharm Sci 2018; 8: 78-84.
[http://dx.doi.org/10.7324/JAPS.2018.8713]
[8]
Ladizinski B, Mistry N, Kundu RV. Widespread use of toxic skin lightening compounds: Medical and psychosocial aspects. Dermatol Clin 2011; 29: 111-23.
[http://dx.doi.org/10.1016/j.det.2010.08.010]
[9]
Fitzpatrick T. Fitzpatrick’s dermatology in general medicine. Freedberg IM , Eisen AZ , Wolff K, Austen F, Goldsmith LA, KatzMed SI, Eds. Argentina: Editorial Medica Panamericana Sa de 2009.
[10]
Bains P. Topical corticosteroid abuse on face: A clinical study of 100 patients. Int J Res Dermatol 2016; 2: 40.
[http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20163105]
[11]
Saraswat A, Lahiri K, Chatterjee M, et al. Topical corticosteroid abuse on the face: A prospective, multicenter study of dermatology outpatients. Indian J Dermatol Venereol Leprol 2011; 77(2): 160-6.
[http://dx.doi.org/10.4103/0378-6323.77455] [PMID: 21393945]
[12]
Sari RK, Soediro A, Rochman F. The truth behind the decision of consumers in buying counterfeit cosmetics product: A qualitative phenomenological research. J Ilm Bid Akunt dan Manaj 2018; 15: 25.
[http://dx.doi.org/10.31106/jema.v15i2.954]
[13]
Sendrasoa FA, Ranaivo IM, Andrianarison M, et al. Misuse of topical corticosteroids for cosmetic purpose in Antananarivo, Madagascar. BioMed Res Int 2017; 1-4.
[http://dx.doi.org/10.1155/2017/9637083] [PMID: 28904977]
[14]
Cristaudo A, D’Ilio S, Gallinella B, et al. Use of potentially harmful skin-lightening products among immigrant women in Rome, Italy: a pilot study. Dermatology (Basel) 2013; 226(3): 200-6.
[http://dx.doi.org/10.1159/000348706] [PMID: 23751225]
[15]
Dey VK. Misuse of topical corticosteroids: A clinical study of adverse effects. Indian Dermatol Online J 2014; 5(4): 436-40.
[http://dx.doi.org/10.4103/2229-5178.142486] [PMID: 25396124]
[16]
Al-Dhalimi MA, Aljawahiry N. Misuse of topical corticosteroids: A clinical study in an Iraqi hospital. East Mediterr Health J 2006; 12(6): 847-52.
[PMID: 17333832]
[17]
Aljunaiyeh H, Naif A, Kadhim K. Non-prescription skin lightening preparations; their use & hazards in Iraq. Int J Pharm Res Allied Sci 2018; 7(2): 209-17.
[18]
Ghosh SK, Dutta A, Sarkar S, Nag SS, Biswas SK, Mandal P. Focal dermal hypoplasia (Goltz Syndrome): A cross-sectional study from Eastern India. Indian J Dermatol 2017; 62(5): 498-504.
[PMID: 28979012]
[19]
Alghamdi KM. The use of topical bleaching agents among women: a cross-sectional study of knowledge, attitude and practices. J Eur Acad Dermatol Venereol 2010; 24(10): 1214-9.
[http://dx.doi.org/10.1111/j.1468-3083.2010.03629.x] [PMID: 20236376]
[20]
Rogers PJ, Wood SM, Garrett EL, et al. Use of nonprescription topical steroids: Patients’ experiences. Br J Dermatol 2005; 152(6): 1193-8.
[http://dx.doi.org/10.1111/j.1365-2133.2005.06513.x] [PMID: 15948981]
[21]
Meena S, Gupta LK, Khare AK, et al. Topical corticosteroids abuse: A clinical study of cutaneous adverse effects. Indian J Dermatol 2017; 62(6): 675.
[http://dx.doi.org/www.e-ijd.org/text.asp?2017/62/6/567/219232] [PMID: 29263550]
[22]
Gupta M. Topical corticosteroid abuse – a prospective clinico-epidemiological study. Our Dermatol Online 2019; 10(2): 142-4.
[http://dx.doi.org/10.7241/ourd.20192.7]
[23]
Nam YS, Kwon IK, Lee KB. Monitoring of clobetasol propionate and betamethasone dipropionate as undeclared steroids in cosmetic products manufactured in Korea. Forensic Sci Int 2011; 210(1-3): 144-8.
[http://dx.doi.org/10.1016/j.forsciint.2011.02.027] [PMID: 21474261]
[24]
Kourouma S, Gbery IP, Kaloga M, et al. Cutaneous depigmentation in black female population for cosmetic purposes: Results of a KAP survey conducted in Abidjan (Ivory Coast). Pan Afr Med J 2016; 24: 159.
[PMID: 27795757] [http://dx.doi.org/10.11604/pamj.2016.24.159.8315]

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