Abstract
This review describes recent advances in the development of DNA- photocleavage agents. Major mechanisms of photosensitized DNA photocleavage are presented and the most popular categories of compounds are considered, which include metal complexes and many organic functional derivatives. DNA-targeted conjugates of photosensitizers are also described and discussed.
Current Pharmaceutical Design
Title: DNA-Photocleavage Agents
Volume: 7 Issue: 17
Author(s): Tatiana Da Ros, Giampiero Spalluto, Alexandre S. Boutorine, Rene V. Bensasson and Maurizio Prato
Affiliation:
Abstract: This review describes recent advances in the development of DNA- photocleavage agents. Major mechanisms of photosensitized DNA photocleavage are presented and the most popular categories of compounds are considered, which include metal complexes and many organic functional derivatives. DNA-targeted conjugates of photosensitizers are also described and discussed.
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Cite this article as:
Tatiana Da Ros , Giampiero Spalluto , Alexandre S. Boutorine , Rene V. Bensasson and Maurizio Prato , DNA-Photocleavage Agents, Current Pharmaceutical Design 2001; 7 (17) . https://dx.doi.org/10.2174/1381612013397140
DOI https://dx.doi.org/10.2174/1381612013397140 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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