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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

DNA-Photocleavage Agents

Author(s): Tatiana Da Ros, Giampiero Spalluto, Alexandre S. Boutorine, Rene V. Bensasson and Maurizio Prato

Volume 7, Issue 17, 2001

Page: [1781 - 1821] Pages: 41

DOI: 10.2174/1381612013397140

Price: $65

Abstract

This review describes recent advances in the development of DNA- photocleavage agents. Major mechanisms of photosensitized DNA photocleavage are presented and the most popular categories of compounds are considered, which include metal complexes and many organic functional derivatives. DNA-targeted conjugates of photosensitizers are also described and discussed.


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